Dr. Cabral's Clinical Formula · Used in Practice for 20+ Years · Shop Now →

The enzyme combination your cardiovascular system has been waiting for, and why Nattokinase alone is only half the story.

36.6%

Arterial plaque reduction ​in ~6 months

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By your 40s, decades of inflammation, oxidized fats, microplastics, and chronic stress have quietly left their mark on your arteries. Fibrin — a sticky, web-like protein — starts accumulating in your blood. Plaque builds along arterial walls. Circulation slows. Energy drops. And most people have no idea it's happening.​

You may have heard about nattokinase going viral. But what the social media posts don't tell you is that it works best when paired with serrapeptase — the two enzymes addressing both the plaque and the inflammation that created it. That's exactly what EquiLife's Proteolytic Enzymes formula is designed to do.
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​Below are the 5 reasons I believe everyone over 40 should be taking this powerful supplement.

01

"We know that nattokinase reduces arterial plaque — literally atherosclerosis — by about 36.6% in just over six months. Statins, only about 11.5%. 300% better from a natural enzyme." — Dr. Stephen Cabral

02

Under a microscope, fibrin looks like fine hairs floating through your bloodstream. This protein — a byproduct of the clotting process — is supposed to be temporary. But chronic inflammation, toxin exposure, and aging cause fibrin to accumulate faster than your body can clear it.

The result? Sluggish blood flow. Thicker blood. Elevated blood pressure. A greater risk of clots. And a subtle but persistent drag on energy, mental clarity, cognitive function, and recovery.

Nattokinase directly dissolves fibrin. It's measured in fibrin units (FUs), and the clinical dosage — 10,000 FUs — is exactly what's in this formula. Dr. Cabral used live blood microscopy with his Boston-area clients and could visually confirm meaningful fibrin reduction within 6 to 8 weeks of supplementation.

Better blood viscosity also means better delivery of oxygen and nutrients to every organ, tissue, and cell — which shows up as improved energy, sharper focus, faster recovery, and healthier-looking skin.

03

Here's the part most viral posts leave out: fibrin and plaque are symptoms — not causes. The underlying driver is chronic inflammation, and if you only address the fibrin without taming the inflammation that produced it, you're fighting an ongoing battle with one hand tied behind your back.

That's where serrapeptase comes in. Derived from enzymes originally found in silkworms, serrapeptase acts as what Dr. Cabral calls "the inflammation cleaner." It breaks down dead and necrotic tissue, helps clear abnormal masses, and powerfully modulates systemic inflammation — in joints, sinuses, the arterial wall, and beyond.

Serrapeptase has been studied extensively for post-surgical recovery, autoimmune conditions, joint health, and sinus support. The clinical minimum is 15,000 SPUs (serrapeptase units), delivered in this formula.

Using only nattokinase is like mopping a wet floor without turning off the tap. Serrapeptase addresses the source — inflammation — so nattokinase can do its job clearing the result.

04

This formula earns the name "proteolytic" for a reason. The added protease enzymes in this upgraded formula aren't specific to the cardiovascular system. Taken on an empty stomach, they circulate systemically and break down abnormal proteins wherever they find them: in the blood, around inflamed joints, in the sinuses, and even proteins that have leaked through a compromised gut lining into circulation.

Joint comfort: Serrapeptase has decades of clinical research behind its use in reducing joint swelling and inflammation — making this formula especially popular among those with arthritis, autoimmune, or injury-related joint issues.

Sinus health: Both nattokinase and serrapeptase help break down excess mucus and reduce sinus inflammation — many users report noticeable improvements in sinus congestion and seasonal discomfort.

Autoimmune and chronic conditions: Reducing systemic inflammatory burden is a cornerstone approach for virtually every chronic condition. Proteolytic enzymes have been foundational in Dr. Cabral's clinical work for over two decades.

The rutin in this formula adds yet another layer — a bioflavonoid antioxidant that reinforces capillary walls, scavenges free radicals, and supports overall vascular integrity from a complementary angle.

05

Arterial health is one of the strongest predictors of healthspan — not just how long you live, but how well you live. The research on nattokinase and serrapeptase shows meaningful, measurable shifts in some of the most critical biomarkers of aging: plaque burden, blood viscosity, LDL and oxidized cholesterol, and inflammatory markers.

Dr. Cabral recommends treating this as a minimum 6-to-12-month commitment. At the 6-month mark, you can recheck your arterial health markers and see the improvements reflected in your labs. Most people notice meaningful shifts in how they feel — energy, circulation, joint comfort, mental clarity — well before that.

Whether you're 35 and proactively building a foundation, or 55 and working to reverse decades of arterial accumulation, this is one of the highest-leverage additions you can make to your daily protocol.

At 35–40, you're preventing. At 50+, you're reversing. Either way, proteolytic enzymes are doing exactly what your body needs them to do — and the earlier you start, the more dramatic the results.

Clinically dosed. No fillers. Every ingredient earns its place.

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The Blood Cleaner

10,000 Fibrin Units (FU)

Dissolves fibrin, reduces arterial plaque, supports healthy blood pressure and lipid levels. Extracted from fermented soy — no soy residue remains in the final enzyme.

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The System Cleaner

Broad-spectrum proteolytic enzymes

Protein-dissolving enzymes that circulate systemically when taken on an empty stomach, clearing abnormal proteins from blood and tissues throughout the body.

Take 2 capsules on an empty stomach upon waking — before food or coffee — so the enzymes enter circulation rather than being used for digestion. Commit to a minimum of 6 to 12 months for meaningful arterial changes, with labs at the 6-month mark to confirm progress. Consult your doctor if you're on blood thinners.

10,000 FU Nattokinase 15,000+ SPU Serrapeptase Take 2 capsules upon waking Empty stomach — before food 6–12 months recommended

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Real results from real customers — verified EquiLife purchasers.

★★★★★

I'm taking Foundational Level 3 supplements, Cell Boost, and Advanced Cell Force already and these have helped rebalance my body. Honestly, I can't tell much of a difference yet (I just started taking them about 1 month ago) but just knowing what the ingredients are and what they do and who formulated them is all I need in order to use them!!!

Kenda D.

Verified Purchaser · Lake City, FL, US

Join thousands of people who've made proteolytic enzymes a cornerstone of their daily health protocol. Formulated by Dr. Cabral, backed by two decades of clinical use and published research.

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Join thousands of people who've made proteolytic enzymes a cornerstone of their daily health protocol. Formulated by Dr. Cabral, backed by two decades of clinical use and published research.

Everything you need to know before you start.

Buy in bulk & save 30% · 60-day guarantee

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Statistical claims referenced reflect published peer-reviewed research on the individual ingredients (nattokinase, serrapeptase). Individual results may vary. Always consult your physician before beginning any new supplement regimen, particularly if you are taking anticoagulants, blood thinners, or other cardiovascular medications.